The International Society of Anti-Infective Pharmacology is an interdisciplinary scientific society for the study of pharmacodynamics and pharmacokinetics and for the improvement of dosing of anti-infectives. The Society efforts are focused on expanding basic and applied knowledge in this area of chemotherapeutics through the organization of symposia, discussion workshops , and educational workshops with international participation, in connection with major scientific meetings dealing with the chemotherapy of infectious diseases (ICAAC, ICC, ECCMID ...), and other scientific societies with common interests, and Regulatory Authorities (FDA, EMEA). The current membership of the Society is about 120 worldwide.
Organization
Past activities and documents
 Membership/Services

Post-ICAAC symposium

Date: Tuesday, September 15, 2009

Venue: Fort Mason Conference Center (Marina Blvd & Buchanan St, San Francisco)

Registration on site:

- ISAP members: free
- Students: free
- Non-members: $100 including one year ISAP membership, beverages, coffee, cookies


 

Program

12:00 am – 1:15 pm ISAP General Meeting and election of Committee members
1.30 - 2.30 pm

Scientific presentation and discussion

Protein binding – do we ever learn?
U. Theuretzbacher: Introductory presentation (methodology issues, relevance of protein binding, open questions, roadmap for future studies, towards a consensus)
M. Zeitlinger: Late-breaking results
Discussion
2.30 - 3.00 pm Break / informal discussion
3.00 – 5.00 pm Scientific presentations by junior investigators
5.00 – 5.30 pm Closing remarks and travel award presentation

Scientific presentations by junior investigators

3:00 pm S. Lemaire
Univ. Catholique de Louvain, Brussels, Belgium		 Torezolid (TR-700), a Novel Methyltetrazolyl-oxazolidinone, Accumulates Markedly within Human THP-1 Macrophages and Shows Activity towards Intraphagocytic Legionella pneumophila
3:20 pm F. Van Bambeke
Univ. Catholique de Louvain, Brussels, Belgium		 Radezolid , a New Oxazolidinone, is Active Against Intraphagocytic Staphylococcus aureus with Various Resistance Phenotypes in a Model of THP-1 Human Macrophages
3:40 pm B.Wu
Univ. of Florida		 Utilizing Mechanism-Based Pharmacokinetic/Pharmacodynamic Models to Understand and Prevent Antimicrobial Resistance
4:00 pm R. Sauermann
Univ. of Vienna		 Abscess penetration of cefpirome in humans
4:20 pm M. Sahre
Univ. of Florida		 Evaluation of Tissue Distribution of TR-701 in Healthy Volunteers, Using Microdialysis
4:40 pm RV. Dudhani
Monash Univ., Australia		 Concentration-dependent Plasma Binding (PB) of Colistin (C): Impacts of Infection, Neutropenia & Multiple Proteins


Directions:

Public Transportation:
Take Bus 91 (towards 19th Ave & Holloway Ave) at Howard St & 3rd St.
Off Board: NE Corner of Lombard St & Laguna St (15 min ride)
Walk to Fort Mason Center (10 min walk)

Taxi: 3.5m, approximately 15 min.

 

More ISAP activities:

ICAAC workshops
Post-ICAAC symposium
ECCMID workshop
Post-ECCMID symposium

Friday, September 11, 2009, at the Hilton San Francisco, 333 O'Farrell Street, San Francisco, CA

ICAAC

Tuesday, September 15, 2009 in San Francisco, CA, afternoon

More information

Saturday, 10 April, 2010, at the Austria Center Vienna

ECCMID

 Tuesday, April 13, 2010 in Vienna, Austria, afternoon
Workshop 1
Basics of Pharmacokinetics and Pharmacodynamics of Anti-infective Agents
(half-day, morning)
Conveners:
Johan W. Mouton, MD, PhD; Canisius Wilhelmina Ziekenhuis, Nijmegen, Netherlands.
Hartmut Derendorf, PhD; Univ. of Florida, Gainesville, FL.
Workshop 2
Clinical Relevance of Pharmacokinetics and Pharmacodynamics of Anti-infective Agents
(half-day, afternoon)
Conveners:
Johan W. Mouton, MD, PhD; Canisius Wilhelmina Ziekenhuis, Nijmegen, Netherlands
Ursula Theuretzbacher, PhD; Center for Anti-Infective Agents, Vienna, Austria
Workshop 3
Inroduction to PK/PD Modeling of Anti-infective Agents
(half-day, morning)
Convener:
Vincent Tam, PhD; Univ. of Houston, TX
Alexander Vinks, PhD; Cincinnati, OH
Workshop 4
Advanced PK/PD Modeling of Anti-infective Agents
(half-day, afternoon)
Convener:
George Drusano, MD; Ordway Research, Albany
Hartmut Derendorf, PhD; University of Florida, Gainesville, FL

 Agenda: The symposium is organized into two complementary serial tracks.
The first track focuses on recent research thoughts and trends regarding protein binding. After a brief introduction we plan an open discussion.
The second track provides a forum for young investigators to discuss their studies via a brief presentation. Topics on protein binding as well as other topics related to PK/PD are eligible and encouraged for submission. The agenda provides time for discussion after each presentation. Don't miss the opportunity to get insightful and motivating feedback.
At the closing of the symposium, the ISAP travel award for the best presentation will be made.
Abstracts are due by July 12. For more information and submission please contact Vincent Tam

Workshop
Optimizing treatment using a pharmacodynamic approach: an interactive workshop using clinical cases

Topics: PK/PD+resistance, protein binding, translational aspects of PK/PD and PK/PD+potentiator combinations.
Also, you won't want to miss the insider's Viennese evening that we are planning for after the symposium!